Each checklist item of the TRIPOD Statement is explained in detail and accompanied by published examples of good reporting. This explanation and elaboration document describes the rationale clarifies the meaning of each item and discusses why transparent reporting is important, with a view to assessing risk of bias and clinical usefulness of the prediction model. The TRIPOD Statement aims to improve the transparency of the reporting of a prediction model study regardless of the study methods used. The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the reporting of studies developing, validating, or updating a prediction model, whether for diagnostic or prognostic purposes. Collins.įor members of the TRIPOD Group, see the Appendix. Collins.Ĭollection and assembly of data: K.G.M. Collins.Īdministrative, technical, or logistic support: K.G.M. Provision of study materials or patients: K.G.M. Collins.įinal approval of the article: K.G.M. Collins.Ĭritical revision of the article for important intellectual content: K.G.M. Collins.Īnalysis and interpretation of the data: K.G.M. Ransohoff: Departments of Medicine and Epidemiology, University of North Carolina at Chapel Hill, 4103 Bioinformatics, CB 7080, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7080.Īuthor Contributions: Conception and design: K.G.M. Vickers: Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 307 East 63rd Street, 2nd Floor, Box 44, New York, NY 10065.ĭr. Steyerberg: Department of Public Health, Erasmus MC–University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, the Netherlands.ĭr. Macaskill: Screening and Test Evaluation Program (STEP), School of Public Health, Edward Ford Building (A27), Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.ĭr. Ioannidis: Stanford Prevention Research Center, School of Medicine, Stanford University, 291 Campus Drive, Room LK3C02, Li Ka Shing Building, 3rd Floor, Stanford, CA 94305-5101.ĭr. Altman and Collins: Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford OX3 7LD, United Kingdom.ĭr. Moons and Reitsma: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, the Netherlands.ĭrs. Moons, PhD, Julius Centre for Health Sciences and Primary Care, UMC Utrecht, PO Box 85500, 3508 GA Utrecht, the Netherlands e-mail, K. Altman is a member of the Medical Research Council Prognosis Research Strategy (PROGRESS) Partnership (G0902393/99558).Ĭorresponding Author: Karel G.M. Collins and Altman are funded in part by the Medical Research Council (grant G1100513). Altman, Cancer Research UK (grant C5529), and the Netherlands Organization for Scientific Research (ZONMW 94). The consensus meeting in June 2011 was partially funded by a National Institute for Health Research Senior Investigator Award held by Dr. Screening and Test Evaluation Program (STEP), School of Public Health, Sydney Medical School, University of Sydney, Sydney, Australia Erasmus MC–University Medical Center Rotterdam, Rotterdam, the Netherlands Memorial Sloan Kettering Cancer Center, New York, New York and University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ĭisclosures: Disclosures can be viewed at Grant Support: There was no explicit funding for the development of this checklist and guidance document. From Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom Stanford Prevention Research Center, School of Medicine, School of Humanities and Sciences, and Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, California
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